Molecular Virology
Oncolytic Herpes Viruses
retargeted to cancer-specific receptors
European Reserch Council - Alma Mater Studiorum università di Bologna

Laura Menotti

Laura Menotti

Present position: Assistant Professor

Education and Training

Institution and Location Degree Years Field of study
University of Pisa, Italy B.S. 1989-1994 Biology
University of Bologna, Italy Ph.D. 1994-1998 Molecular Virology

Positions and Employment

1999 - 2002 Postdoctoral fellow (Assegno di Ricerca), Section of Microbiology and Virology, Department of Experimental Pathology, University of Bologna, Italy.
2002 - present Assistant Professor (Ricercatore), University of Bologna, Italy.
until 15-10-2012 Department of Experimental Pathology - Section of Microbiology and Virology, University of Bologna, Italy.
since 16-10-2012 Department of Pharmacy and BioTechnology (FaBiT), University of Bologna, Italy.

Experiences in other laboratories and abroad

1997 IRBM, Istitute for Biomolecular Research "P. Angeletti", Pomezia (RM), Italy (as Visiting Graduate Student).
1997-1998 "Mario Negri" Instute for Pharmacological Research, Milan, Italy (as Visiting Graduate Student).
1999 >Kovler Viral Oncology Laboratories, University of Chicago, USA (3 months as Visiting Research Associate).
2006 Institut für Virologie, Heirich Heine Universität Düsseldorf, Germany (3 months as FEMS-ESCMID Research Fellow).
2009-2011   SC. Trasferimento Genico IST- Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy (for scientific collaboration).
2012-2013   AMI - Adolphe Merkle Institute, Marly (Fribourg), Switzerland (9 months as Visiting Scientist).

Awards and Fellowships

1999 Award for PhD Thesis from the SIMGBM (Italian Society of General Microbiology and Microbial Biotechnologies).
2006 Joint FEMS-ESCMID Research Fellowship 2006, for research on: "Generation of recombinant viruses retargeted to tumor cells for the design of oncolytic herpesviruses".
2009 Award by the Fondazione Adriano Buzzati-Traverso (FABT), Fondo Giovanni Magni, for the paper Proc Natl Acad Sci USA 106(22):9039-44.

Grants as PI

30-11-2001, 1 year Giovani Ricercatori e.f. 2000 - Università di Bologna. Title: "Basi molecolari dell'interazione della glicoproteina D del virus herpes simplex con i recettori cellulari nectina1 umana e murina"
10-7-2001, 1 year CNR-Agenzia 2000 Giovani Ricercatori. Title: "Trasduzione del segnale e fosforilazione del recettore hNectin1 indotti dall'interazione con il virus herpes simplex e con la glicoproteina virale gD"
2004-2011, yearly Co-Proponent of "Roberto Pallotti" and "Cornelia Pallotti" grants for oncological research, of the Department of Experimental Pathology, University of Bologna
2005-2011, yearly RFO-Ex 60% University of Bologna
30-01-2006, 2 years PRIN 2005. Title: "Sviluppo di nuove strategie terapeutiche contro le infezioni da herpesvirus e papillomavirus umani e patologie correlate"
22-11-2010, 3 years Programma di Ricerca Sanitaria Finalizzata 2008 - Bando Giovani Ricercatori 2008 (GR-2008-1135643) del Ministero della Salute. Title: "In vivo screening for genes inducing neural tumors and development of animal models for assaying innovative therapies for gliomas"

Editorial Activity

2006-- Referee for Future Virology, Molecular Oncology (Elsevier), Virology Journal

Scientific Societies Membership

since 2000 SIMGBM (Italian Society of General Microbiology and Microbial Biotechnologies).
since 2001 SIV (Italian Society of Virology).
since 2009 European Society for Virology (ESV).

Teaching

2003 - present In charge of the "Laboratory of General Microbiology" course for the three-year Degree in Biotechnology at the University of Bologna.
2003 - 2012 Seminar-Lectures in the "General Microbiology" and "Molecular Virology" courses course in the three-year Degree in Biotechnology at the University of Bologna.
2005 - 2006 Organization and supervision of the “Laboratory of Molecular Virology” for the two-year Specialization (Master) Degree in Molecular and Industrial Biotechnology at the University of Bologna.

Acknowledgments for teaching

2004 - 2005 Encomium of the Dean of the University of Bologna for the "highest overall students' appreciation for the Laboratory of General Microbiology course".